From A12 motorway take Pisa centro/aeroporto exit, drive on after the toll towards Firenze and take the 2nd Pontedera exit. At the roundabout follow direction to Peccioli and then Fabbrica. When you are at Fabbrica, follow direction Montelopio (via di Mezzo) and after about 700 metres you will find the B&B signpost.
From A1 motorway take Firenze Scandicci exit, follow directions to Pisa/Livorno, take the 1st Pontedera exit, then as above.
Closest airport: Pisa Galileo Galilei (45 minutes by car)